Fig. 4

Male patient, 27 years old, diagnosed with NHL (DLBCL). His international prognostic risk category was low-intermediate risk. He received 6 cycles of chemotherapy. First (interim) PET/CT (hepatic reference 2.1) axial CT (A), axial MIP (B), axial fused PET/CT (C), sagittal CT (D), sagittal MIP (E) and sagittal fused PET/CT (F) images show metabolically active left inguinal LNs measuring (blue arrow) about 0.7 cm in short axis and achieving SUVmax 2.5 as well as multiple low metabolically active bone infiltrates (osteolytic and sclerotic) affecting multiple vertebral levels and sternum, the most active one (11th dorsal vertebral body) achieving SUVmax 2.8. The patient received 6 cycles of chemotherapy. Second (interim) PET/CT (hepatic reference 2.2) axial CT (A), axial MIP (B), axial fused PET/CT (C), sagittal CT (D), sagittal MIP (E) and sagittal fused PET/CT (F) images show complete metabolic resolution with of left inguinal LN (blue arrow) as well as the prior reported bony infiltrates. It was reported as complete response with Deauville score 2