Fig. 5

Male patient, 39 years old, diagnosed with stage II NHL. His international risk category was low intermediate. He received first 4 cycles of chemotherapy. First (interim) PET/CT (hepatic reference 2.5); axial CT (A) & axial fused PET/CT (B) images show metabolically active right submandibular LN measuring about 1.5 cm in short axis and achieving SUVmax 4 (blue arrow). FNAC was done confirming the presence of malignant process. Patient resumed chemotherapy cycles and after 3 more cycles. Second (interim) PET/CT (hepatic reference 2.3); axial CT (A & C) and axial fused PET/CT (B & D) images show newly developed multiple bilateral upper deep cervical LNs, the most active left submandibular LN (yellow arrow) achieving SUVmax 12.3 and measuring about 1.2 cm in short axis. It was reported as progressive disease with Deauville score 5