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Table 4 Comparison between the benign group and malignant group regarding composition, echogenicity, shape, margins of thyroid nodules, and presence of echogenic foci in the thyroid nodules

From: A practical trial to use Thyroid Imaging Reporting and Data System (TI-RADS) in differentiation between benign and malignant thyroid nodules

 

Benign group

Malignant group

Test value

P value

Sig.

No. = 31

No. = 9

Composition

 Cystic or almost completely cystic (0 points)

13 (41.9%)

0 (0.0%)

5.591

0.018

S

 Spongiform (0 points)

2 (6.5%)

0 (0.0%)

0.611

0.434

NS

 Mixed cystic and solid (1 point)

13 (41.9%)

0 (0.0%)

5.591

0.018

S

 Solid or almost completely solid (2 points)

3 (41.9%)

9 (88.9%)

27.097

0.000

HS

Echogenicity

 Anechoic (0 points)

12 (38.7%)

0 (0.0%)

4.977

0.025

S

 Hyperechoic (1 point)

11 (35.5%)

0 (0.0%)

4.405

0.036

S

 Isoechoic (1 point)

7 (22.6%)

5 (55.6%)

3.612

0.057

NS

 Hypoechoic (2 points)

1 (3.2%)

1 (11.1%)

0.913

0.339

NS

 Very hypoechoic (3 points)

0 (0.0%)

3 (33.3%)

11.171

0.001

HS

Shape

 Wider than taller (0 points)

31 (100.0%)

6 (66.7%)

11.171

0.001

HS

 Taller than wider (3 points)

0 (0.0%)

3 (33.3%)

11.171

0.001

HS

Margins

 Smooth (0 points)

20 (64.5%)

1 (11.1%)

7.977

0.005

HS

 Ill-defined (0 points)

11 (35.5%)

0 (0.0%)

4.405

0.036

S

 Lobulated or irregular (2 points)

0 (0.0%)

6 (66.7%)

24.314

0.000

HS

 Extrathyroidal extension (3 points)

0 (0.0%)

2 (22.2%)

7.251

0.007

HS

Presence of echogenic foci

 None (0 points)

17 (54.8%)

1 (11.1%)

5.389

0.020

S

 Large comet tail artifacts (0 points)

10 (32.3%)

0 (0.0%)

3.871

0.049

S

 Macrocalcifications (1 point)

4 (12.9%)

1 (11.1%)

0.020

0.886

NS

 Peripheral (rim) calcifications (2 points)

1 (3.2%)

1 (11.1%)

0.913

0.339

NS

 Punctuate echogenic foci (3 points)

1 (3.2%)

6 (66.7%)

12.991

0.000

HS