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Table 4 Comparison between the benign group and malignant group regarding composition, echogenicity, shape, margins of thyroid nodules, and presence of echogenic foci in the thyroid nodules

From: A practical trial to use Thyroid Imaging Reporting and Data System (TI-RADS) in differentiation between benign and malignant thyroid nodules

  Benign group Malignant group Test value P value Sig.
No. = 31 No. = 9
Composition
 Cystic or almost completely cystic (0 points) 13 (41.9%) 0 (0.0%) 5.591 0.018 S
 Spongiform (0 points) 2 (6.5%) 0 (0.0%) 0.611 0.434 NS
 Mixed cystic and solid (1 point) 13 (41.9%) 0 (0.0%) 5.591 0.018 S
 Solid or almost completely solid (2 points) 3 (41.9%) 9 (88.9%) 27.097 0.000 HS
Echogenicity
 Anechoic (0 points) 12 (38.7%) 0 (0.0%) 4.977 0.025 S
 Hyperechoic (1 point) 11 (35.5%) 0 (0.0%) 4.405 0.036 S
 Isoechoic (1 point) 7 (22.6%) 5 (55.6%) 3.612 0.057 NS
 Hypoechoic (2 points) 1 (3.2%) 1 (11.1%) 0.913 0.339 NS
 Very hypoechoic (3 points) 0 (0.0%) 3 (33.3%) 11.171 0.001 HS
Shape
 Wider than taller (0 points) 31 (100.0%) 6 (66.7%) 11.171 0.001 HS
 Taller than wider (3 points) 0 (0.0%) 3 (33.3%) 11.171 0.001 HS
Margins
 Smooth (0 points) 20 (64.5%) 1 (11.1%) 7.977 0.005 HS
 Ill-defined (0 points) 11 (35.5%) 0 (0.0%) 4.405 0.036 S
 Lobulated or irregular (2 points) 0 (0.0%) 6 (66.7%) 24.314 0.000 HS
 Extrathyroidal extension (3 points) 0 (0.0%) 2 (22.2%) 7.251 0.007 HS
Presence of echogenic foci
 None (0 points) 17 (54.8%) 1 (11.1%) 5.389 0.020 S
 Large comet tail artifacts (0 points) 10 (32.3%) 0 (0.0%) 3.871 0.049 S
 Macrocalcifications (1 point) 4 (12.9%) 1 (11.1%) 0.020 0.886 NS
 Peripheral (rim) calcifications (2 points) 1 (3.2%) 1 (11.1%) 0.913 0.339 NS
 Punctuate echogenic foci (3 points) 1 (3.2%) 6 (66.7%) 12.991 0.000 HS