Multiple sclerosis and depressive manifestations: can diffusion tensor MR imaging help in the detection of microstructural white matter changes?

Egyptian Journal of Radiology and Nuclear Medicine

Table 1 Illustrates the mean FA values of the examined white matter tracts in different study groups and statistical results

	Mean FA value (±SD)			DMS vs nDMS, P value	nDMS vs HC, P value	DMS vs HC, P value
	DMS (n = 20)	nDMS (n = 10)	HC (n = 10)	DMS vs nDMS, P value	nDMS vs HC, P value	DMS vs HC, P value
Right cingulum	0.5690 (0.0529)	0.6220 (0.0444)	0.6690 (0.0431)	0.0111	0.0273	0.0001
Left cingulum	0.5660 (0.0811)	0.6350 (0.0232)	0.6740 (0.0313)	0.0142	0.0054	0.0004
Right uncinate fasciculus	0.4035 (0.0673)	0.5250 (0.0425)	0.5300 (0.0450)	0.0001	0.8012	0.0001
Left uncinate fasciculus	0.4485 (0.0825)	0.5310 (0.0522)	0.5220 (0.0543)	0.0076	0.7099	0.0168
Right fornix	0.3820 (0.0711)	0.5070 (0.0419)	0.5090 (0.0398)	0.0001	0.9141	0.0001
Left fornix	0.3435 (0.0587)	0.4610 (0.0536)	0.4770 (0.0343)	0.0001	0.4373	0.0001
Right anterior thalamic radiation	0.5815 (0.0939)	0.6120 (0.0266)	0.6230 (0.0445)	0.3264	0.5106	0.1985
Left anterior thalamic radiation	0.5775 (0.1057)	0.6290 (0.0557)	0.6150 (0.0395)	0.1622	0.5248	0.2907

DMS patients with depression and MS, nDMS patients without depression and with MS, HC healthy control, n number of patients