Table 2 Miller-Payne grading system
Grade | Histopathology findings |
|---|---|
Grade 1 | No change or some alteration to individual malignant cells, but no reduction in overall cellularity |
Grade 2 | Minor loss of tumor cells, but overall cellularity still high; up to 30% |
Grade 3 | Between an estimated 30–90% reduction in tumor cells |
Grade 4 | Marked disappearance of tumor cells such that only small clusters or widely dispersed individual cells remain; more than 90% loss of tumor cells |
Grade 5 | No malignant cells identifiable in sections from the site of the tumor; only vascular fibro-elastic stroma remains often containing macrophages. However, DCIS may be present |