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Table 2 Analysis of the lesion load measurement and relative comparisons of DIR versus T2 and DIR versus FLAIR sequences

From: Diagnostic accuracy of double inversion recovery in delineation of multiple sclerosis lesions and its clinical correlation with expanded disability scoring system

RegionDIRT2FLAIRRelative ratio (%)
DIR/T2 (%)P valueDIR/FLAIR (%)P value
PVWM12.6 ± 3.9
13 (0–41)
9.6 ± 3.1
7.5 (0–35)
12.1 ± 4.1
8.5 (0–37)
31%0.033*4%0.927
DWM10.2 ± 3.8
8 (1.0–34)
10.3 ± 3.5
10.0 (0–38)
10.4 ± 3.3
9.0 (0–34)
− 1%0.834− 3%0.619
Mixed W-GM9.1 ± 3
8 (0–25)
6.2 ± 2.7
5.00 (0–21)
7.3 ± 2.1
6.0 (1.0–23)
47%< 0.001**24%0.009*
JC9.1 ± 2.6
6 (0–22)
9.6 ± 2.1
5.00 (0–25)
10 ± 2.2
6.0 (0–21)
− 2%0.696− 5%0.622
Cortical1.5 ± 0.8
1 (0–9)
0.6 ± 0.2
0.0 (0–7)
0.8 ± 0.2
0 (0–7.0)
98%0.003*80%0.004*
IT1.9 ± 0.5
2.0 (0–15)
1.5 ± 0.3
1.0 (0–9)
1.2 ± 0.3
1.0 (0–8.0)
39%0.023*63%0.002*
Total41.9 ± 13.4
52 (6–121)
35 ± 9.6
31.5 (3–107)
38.7 ± 12.4
33.5 (4–114)
18%0.003*7%0.039*
  1. Data were expressed as mean ± SD and median (range)
  2. P probability
  3. *Statistically significant p < 0.05
  4. **Highly significant p < 0.001