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Table 2 Analysis of the lesion load measurement and relative comparisons of DIR versus T2 and DIR versus FLAIR sequences

From: Diagnostic accuracy of double inversion recovery in delineation of multiple sclerosis lesions and its clinical correlation with expanded disability scoring system

Region

DIR

T2

FLAIR

Relative ratio (%)

DIR/T2 (%)

P value

DIR/FLAIR (%)

P value

PVWM

12.6 ± 3.9

13 (0–41)

9.6 ± 3.1

7.5 (0–35)

12.1 ± 4.1

8.5 (0–37)

31%

0.033*

4%

0.927

DWM

10.2 ± 3.8

8 (1.0–34)

10.3 ± 3.5

10.0 (0–38)

10.4 ± 3.3

9.0 (0–34)

− 1%

0.834

− 3%

0.619

Mixed W-GM

9.1 ± 3

8 (0–25)

6.2 ± 2.7

5.00 (0–21)

7.3 ± 2.1

6.0 (1.0–23)

47%

< 0.001**

24%

0.009*

JC

9.1 ± 2.6

6 (0–22)

9.6 ± 2.1

5.00 (0–25)

10 ± 2.2

6.0 (0–21)

− 2%

0.696

− 5%

0.622

Cortical

1.5 ± 0.8

1 (0–9)

0.6 ± 0.2

0.0 (0–7)

0.8 ± 0.2

0 (0–7.0)

98%

0.003*

80%

0.004*

IT

1.9 ± 0.5

2.0 (0–15)

1.5 ± 0.3

1.0 (0–9)

1.2 ± 0.3

1.0 (0–8.0)

39%

0.023*

63%

0.002*

Total

41.9 ± 13.4

52 (6–121)

35 ± 9.6

31.5 (3–107)

38.7 ± 12.4

33.5 (4–114)

18%

0.003*

7%

0.039*

  1. Data were expressed as mean ± SD and median (range)
  2. P probability
  3. *Statistically significant p < 0.05
  4. **Highly significant p < 0.001