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Table 1 Overall accuracy of HSG diagnosis compared to the gold standard test (hysteroscopy ± diagnostic laparoscopy with dye test)

From: The validity of HSG in infertility work up

Number of patientsa

True positive

True negative

False positive

False negative

sensitivity

specificity

PPV

NPV

accuracy

P value

Uterine cavity (n = 200)

         

< 0.02

 Congenital abnormalities of uterine shapeb

29

163

7

1

96.9 (78–97)

95.9 (88–97)

80.6 (58–77)

99.4 (81–99.5)

96 (88–96)

 Luminal filling defect

         

 Submucosa fibroid/polyp

41

147

7

5

89.1 (88–91)

95.5 (89–96)

85.4 (82–89)

96.7 (88–99)

94 (81–94)

 Adhesion

32

158

6

4

88.9 (85–89)

96.3 (88–94)

84.2 (81–85)

97.5 (89–98)

95 (88–95)

 Abnormal uterine contour c

28

166

3

3

90.3 (81–91)

98.2 (86–99)

90.3 (85–92)

96.4 (89–97)

97 (91–97)

Tubal status (n = 128)

         

< 0.04

 Bilateral tubal patency

72

53

1

2

97.3 (89–99)

98.1 (93–99)

98.6 (88–99)

96.6 (81–97)

97.7 (90–98)

 Bilateral obstruction

30

93

3

2

93.8 (87–94)

96.9 (90–97)

90.9 (86–92)

97.9 (90–99)

96.1 (89–98)

 Unilateral obstruction

26

92

6

4

86.7 (81–90)

93.9 (87–95)

81.3.8 (80–90)

95.8 (88–98)

92.2 (89–98)

Peritoneal abnormalities (n = 128)

         

< 0.01

 Peritubal adhesions

12

101

11

4

75 (68–79)

90.2 (83–91)

52.2 (48–57)

96.2 (88–97)

88.3 (80–93

 Pelvic adhesions

26

90

9

3

89.7 (81–90)

90.9 (78–91)

74.3 (68–80)

96.8 (91–98)

90.6 (88–97)

  1. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy data are percentages. All numbers in parentheses are 95% CIs
  2. a200 women underwent hysteroscopy, 128 of them underwent additional laparoscopy with dye test
  3. b29 women was diagnosed to have congenital abnormalities of uterine shape on hysteroscopy (septate uterus in 15, bicornuate in 11, and unicornuate in 3)
  4. c28 women was diagnosed to have abnormal uterine contour on hysteroscopy (adenomyosis in 11 and fibroid uterus in 17 patients)