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Table 1 Overall accuracy of HSG diagnosis compared to the gold standard test (hysteroscopy ± diagnostic laparoscopy with dye test)

From: The validity of HSG in infertility work up

Number of patientsaTrue positiveTrue negativeFalse positiveFalse negativesensitivityspecificityPPVNPVaccuracyP value
Uterine cavity (n = 200)         < 0.02
 Congenital abnormalities of uterine shapeb291637196.9 (78–97)95.9 (88–97)80.6 (58–77)99.4 (81–99.5)96 (88–96)
 Luminal filling defect         
 Submucosa fibroid/polyp411477589.1 (88–91)95.5 (89–96)85.4 (82–89)96.7 (88–99)94 (81–94)
 Adhesion321586488.9 (85–89)96.3 (88–94)84.2 (81–85)97.5 (89–98)95 (88–95)
 Abnormal uterine contour c281663390.3 (81–91)98.2 (86–99)90.3 (85–92)96.4 (89–97)97 (91–97)
Tubal status (n = 128)         < 0.04
 Bilateral tubal patency72531297.3 (89–99)98.1 (93–99)98.6 (88–99)96.6 (81–97)97.7 (90–98)
 Bilateral obstruction30933293.8 (87–94)96.9 (90–97)90.9 (86–92)97.9 (90–99)96.1 (89–98)
 Unilateral obstruction26926486.7 (81–90)93.9 (87–95)81.3.8 (80–90)95.8 (88–98)92.2 (89–98)
Peritoneal abnormalities (n = 128)         < 0.01
 Peritubal adhesions1210111475 (68–79)90.2 (83–91)52.2 (48–57)96.2 (88–97)88.3 (80–93
 Pelvic adhesions26909389.7 (81–90)90.9 (78–91)74.3 (68–80)96.8 (91–98)90.6 (88–97)
  1. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy data are percentages. All numbers in parentheses are 95% CIs
  2. a200 women underwent hysteroscopy, 128 of them underwent additional laparoscopy with dye test
  3. b29 women was diagnosed to have congenital abnormalities of uterine shape on hysteroscopy (septate uterus in 15, bicornuate in 11, and unicornuate in 3)
  4. c28 women was diagnosed to have abnormal uterine contour on hysteroscopy (adenomyosis in 11 and fibroid uterus in 17 patients)