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Table 1 The mean and standard deviation (minimum to maximum) of FA and MD (× 10−3 mm2/s) values of the white matter tracts in patients with severe COPD and the controls

From: Diffusion tensor imaging of white matter integrity in relation to smoking index and exacerbations in severe chronic obstructive pulmonary disease

 

Patients

n = 30

Controls

n = 15

Test of significance

FA

 SLF

0.31 ± 0.06 (0.20–0.43)

0.40 ± 0.04 (0.32–0.48)

p < 0.001*

 IOFF

0.33 ± 0.07 (0.20–0.45)

0.43 ± 0.03 (0.37–0.50)

p < 0.001*

 UF

0.27 ± 0.05 (0.19–0.37)

0.36 ± 0.04 (0.30–0.42)

p < 0.001*

 CING

0.28 ± 0.05 (0.20–0.38)

0.38 ± 0.04 (0.30–0.44)

p < 0.001*

 OR

0.32 ± 0.07 (0.21–0.44)

0.42 ± 0.03 (0.37–0.48)

p < 0.001*

 GCC

0.51 ± 0.08 (0.36–0.63)

0.61 ± 0.06 (0.51–0.72)

p < 0.001*

 SCC

0.50 ± 0.07 (0.38–0.61)

0.63 ± 0.07 (0.52–0.73)

p < 0.001*

MD

 SLF

1.15 ± 0.17 (0.89–1.42)

0.81 ± 0.05 (0.74–0.93)

p < 0.001*

 IOFF

1.11 ± 0.15 (0.84–1.35)

0.80 ± 0.05 (0.71–0.91)

p < 0.001*

 UF

1.18 ± 0.14 (0.95–1.41)

0.86 ± 0.07 (0.78–1.00)

p < 0.001*

 CING

1.17 ± 0.13 (0.94–1.39)

0.83 ± 0.07 (0.73–0.96)

p < 0.001*

 OR

1.08 ± 0.24 (0.10–1.42)

0.84 ± 0.07 (0.74–0.97)

p < 0.001*

 GCC

0.97 ± 0.09 (0.80–1.12)

0.82 ± 0.04 (0.74–0.92)

p < 0.001*

 SCC

0.99 ± 0.11 (0.79–1.21)

0.81 ± 0.04 (0.73–0.90)

p < 0.001*

  1. Footnotes: FA fractional anisotropy, SLF superior longitudinal fasciculus, IOFF inferior occipitofrontal fasciculus, UF uncinate fasciculus, CING cingulate gyrus, OR optic radiation, GCC genu of corpus callosum, SCC splenium of corpus callosum, MD mean diffusivity
  2. *p value of less than 0.05 was considered significant