Fig. 1From: Proton MR spectroscopy in characterization of focal bone lesions of peripheral skeleton21-year-old male patient. a. AP radiograph of the right knee. Irregular lytic lesion (black arrow) in the right proximal tibial epimetaphysis (arrow). b. Lateral radiograph of the right knee. The lesion is more conspicuous and shows cortical destruction (arrow). c. Post-contrast T1weighted axial image showing large destructive lesion with peripheral contrast enhancement. The associated soft tissue is causing popliteal vessel encasement (arrow). d. MRS shows a tall choline peak at 3.2 ppm (arrow). e. HNE 200× showing highly atypical stromal cells laying down osteoid suggestive of osteosarcomaBack to article page