Fig. 2

Consequent stages during the processing of 3D T1-W images in FreeSurfer software. a Conventional coronal image at the hippocampal body level showing mild widening of the choroid fissure and temporal horns. b Axial image showing removal of non-brain tissue followed by subcortical segmentation where there is the identification and outlining of different brain structures including here the hippocampus as a whole organ. c Axial image showing segmentation of the hippocampus into subfields. d Coronal image showing filling of different hippocampal subfields and annotation in different colors. The table is showing calculation of the hippocampal subfield volume done by quantification of the number of voxels