Table 3 Correlation between the volumes of CA1 and subiculum in mm3 in AD patients and MMSE and CDR scores
Mean hippocampal subfield volumes | HC (n = 15) | AD (n = 30) | P value | R score (MMSE/CDR) | ||
|---|---|---|---|---|---|---|
Mild | Moderate | Severe | ||||
Right CA1 | 693.68 + 40.25 | 602.05 + 29.7 | 462.21 + 41.04 | 410.26 + 4.39 | < 0.00001 | 0.9711/− 0.8921 |
Right subiculum | 488.78 + 38.95 | 390.59 + 14.46 | 330.81 + 23.89 | 250.63 + 35.33 | < 0.00001 | 0.9579/− 0.8793 |
Left CA1 | 686.29 + 36.72 | 583.97 + 34.22 | 458.03 + 33.67 | 402.04 + 8.89 | < 0.00001 | 0.9801/− 0.9174 |
Left subiculum | 476.57 + 28.45 | 386.03 + 5.43 | 347.83 + 16.55 | 312.29 + 0.89 | < 0.00001 | 0.9875/− 0.8715 |