Fig. 4

15-yers-old girl with infantile form metachromatic leuckdystrophy. Different sequences MRI revealed bilateral symmetrical confluent foci of high T2 and FLAIR signal in the periventricular white matter (yellow arrows) with no enhancement at contrast series (white arrows in F,G). The periventricular white matter and centrum semiovale showed tigroid patterns of demyelination (yellow arrow in “C” T2WI). Extension of the abnormality into the corpus callosum (yellow arrow in H2) and the internal capsule as well as corticospinal tracts also were noted.