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Table 2 General MRI findings of the selected group patients (n = 60)

From: Reliability of MRI in detection and differentiation of acute neonatal/pediatric encephalopathy causes among neonatal/pediatric intensive care unit patients

DisorderNumberConventional MRI findingsDWI
1. Hypoxic ischemia injury (HII)39 (65%)According to the severityRestricted diffusion in affected areas in acute phase
2. Metachromatic leukodystrophy6 (10%)High T2/FLAIR signal in the deep white matter sparing the U-fibers with tigroid patternRestricted diffusion in affected white matter
3. BTBGD4 (6.7%)High T2/FLAIR signal in both basal ganglia, thalami, and the white matter becomes resolved after treatmentRestricted diffusion in acute phase
4. Leigh disease4 (6.7%)High T2/FLAIR signal in the basal ganglia, thalami, brainstem, and the white matterRestricted diffusion in acute phase
5. Periventricular leukomalacia (PVL)3 (5%)High T2 periventricular foci, minimal blooming at T2* for hemorrhageEarly restricted diffusion with normalization within 5–7 days
6. MELAS2 (3.3%)Multiple subcortical and cortical infarct-like lesions, with variable degrees of generalized cerebellar and cerebral atrophy with frequent involvement of the parietal, occipital, and the basal ganglia.Restricted diffusion in acute phase
7. Non-ketotic hyperglycinemia2 (3.3%)Diffuse high T2 and FLAIR signal of the white matter and the cerebral cortexRestricted diffusion in acute phase