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Table 5 The optimal cut-off values of nADC liver and ADC for each fibrosis stages

From: The diagnostic value of normalized ADC using spleen as reference organ in assessment liver fibrosis

Variable ADC nADC liver
F0 vs F1
Optimal cut-off value 1.55 (×10−3 mm2/s) 1.44
Sensitivity (%) 70% 83%
Specificity (%) 66% 67%
AUC (95% CI) 0.588(379 to 775) 0.717(507 to 874)
F0 vs F2
Optimal cut-off value 1.53 (×10−3 mm2/s) 1.41
Sensitivity (%) 72% 84%
Specificity (%) 55% 66%
AUC (95% CI) 0.617(407 to799) 0.729(520-883)
F0 vs F3
Optimal cut-off value 1.51 (×10−3 mm2/s) 1.4
Sensitivity (%) 80% 80%
Specificity (%) 50% 75%
AUC (95% CI) 0.644(442-818) 0.739(565-902)
F0 vs F4
Optimal cut-off value 1.49 (×10−3 mm2/s) 1.38
Sensitivity (%) 80% 90%
Specificity (%) 72% 80%
AUC (95% CI) 0.648(453-812) 0.879(589-908)