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Table 1 Clinical characteristics of the children diagnosed with ANEC

From: Multi-parametric magnetic resonance imaging in acute necrotizing encephalopathy of children: validity and prognostic value

Stages

NO. of cases

%

1st stage (prodromal stage)

 Respiratory manifestations (e.g., cough/expectoration)

10

33.3%

 GIT manifestations (e.g., vomiting, diarrhea)

6

20%

 Skin manifestations (e.g., erythema)

2

7%

 Fever associated with the previous manifestations

14

47%

 Non-specific febrile illness

12

40%

2nd stage (acute necotizing encephalopathy stage/neurological manifestations)

 Generalized convulsions

18

60%

 Abnormal movements/agitated

14

46.6%

 Disturbed consciousness

18

60%

 Focal deficits

24

80%

 Weak lower limbs

6

20%

 Dysarthria

4

13.3%

 Behavioral changes

8

26.7%

 Diplopia

6

20%

3rd stage (prognosis/follow-up)

 Survived with neurological sequelae

20

67%

 Full recovery

6

20%

 Died

4

13%