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Table 5 Sensitivities, specificities, and accuracies expressed per regions involved

From: Whole body diffusion-weighted MRI in detection of metastasis and lymphoma: a prospective longitudinal clinical study

 

Positive

Negative

Sensitivity

Specificity

PPV

NPV

Accuracy

TP

FP

TN

FN

Value

95% CI

Value

95% CI

Value

95% CI

Value

95% CI

Value

95% CI

LNs (16 regions)

2 × Cervical

26

13

44

9

74

57–88

77

64–87

67

54–77

83

73–90

76

66–84

Mediastinal

10

5

21

10

50

27–73

81

61–93

67

45–83

68

57–77

67

52–80

2 × supra-clavicular

8

7

67

10

44

22–69

91

81–96

53

32–73

87

81–91

82

72–89

2 × axillary

27

18

42

5

84

67–95

70

57–81

60

50–69

89

79–95

75

65–83

Para-aortic

16

1

27

2

89

65–98

96

82–100

94

70–99

93

78–98

93

82–99

Porta-hepatis

9

0

36

1

90

56–100

100

90–100

100

 

97

85–100

98

88–100

Mesenteric

8

3

32

3

73

39–94

91

77–98

73

46–89

91

80–97

87

74–95

2 × iliac

19

5

63

5

79

58–93

93

84–98

79

61–90

93

85–97

89

81–95

2 × femoral

12

9

71

0

100

74–100

89

80–95

57

42–71

100

 

90

82–95

2 × inguinal

19

18

54

1

95

75–100

75

63–84

51

41–61

98

89–100

79

70–87

Total LNs

154

79

457

46

77

71–83

85

82–88

66

61–71

91

88–93

83

80–86

Skeletal system (63 regions)

Skull

11

1

32

2

85

55–98

97

84–100

92

61–99

94

82–98

93

82–99

2 × clavicle

26

8

53

5

84

66–95

87

76–94

76

63–86

91

83–96

86

77–92

Sternum

14

3

26

3

82

57–96

90

73–98

82

61–93

90

75–96

87

74–95

2 × humerus

33

6

49

4

89

75–97

89

87–96

85

72–92

92

83–97

89

81–95

24 × ribs

339

19

718

28

92

89–95

97

96–98

95

92–97

96

95–97

96

94–99

7 × cervical vertebrae

76

17

210

19

80

71–88

93

88–96

82

74–88

92

88–94

89

85–92

12 × dorsal vertebrae

176

19

334

23

88

83–93

95

92–99

90

86–94

94

91–96

92

90–94

5 × lumbar vertebrae

70

16

133

11

86

77–93

89

83–94

81

73–88

92

87–95

88

83–92

Sacrum

15

4

25

2

88

64–99

86

68–96

79

60–91

93

77–98

87

74–95

2 × iliac bones

40

9

38

5

89

76–96

81

67–91

82

71–89

88

77–95

85

76–91

2 × pubic bones

12

1

71

8

60

36–81

99

93–100

92

62–99

90

84–94

90

82–95

2 × femurs

35

11

43

3

92

79–98

80

66–89

76

65–84

93

83–98

85

76–91

2 × tibias

20

3

66

3

87

66–97

96

88–99

87

69–95

96

88–98

93

86–98

Total skeletal metastases

867

117

1798

116

88

86–90

94

93–95

88

86–90

94

93–95

92

91–93

Organs

Brain

7

2

35

2

78

40–97

95

82–99

78

47–93

95

84–98

91

79–98

Lung

14

3

21

8

64

41–83

88

68–97

82

61–93

72

60–82

76

61–87

Liver

16

0

30

0

100

97–100

100

88–100

100

 

100

 

100

92–100

Others

11

1

30

4

73

45–92

97

83–100

92

61–99

88

76–95

89

76–96

Total organ metastasis

48

6

116

14

77

65–87

95

90–98

89

78–95

89

84–93

89

84–93

Total

 

1069

202

2371

176

86

84–88

92

91–93

84

82–86

93

92–94

90

89–91

  1. Abbreviations: LN lymph node, TP true-positive, FP false-positive, TN true-negative, FN false-negative, CI confidence interval, NPV negative predictive value, PPV positive predictive value