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Table 4 Univariate and multivariate logistic regression analysis

From: Role of ultrasound in predicting the molecular subtypes of invasive breast ductal carcinoma

Subtype

Univariate logistic regression analysis

Multivariate logistic regression analysis

Predictive SS

OR (95% C.I.)

P value

Independent predictors

OR (95% C.I.)

P value

Luminal A subtype

Echogenic halo

7.46 (3.69–15.07)

< 0.001*

Echogenic halo

3.56 (1.46–8.69)

0.005*

Posterior shadowing

6.72 (3.30–13.66)

< 0.001*

Posterior shadowing

4.60 (1.78–11.89)

0.002*

Angular or spiculated margin

4.65 (2.37–9.12)

< 0.001*

Angular or spiculated margin

1.65 (0.66–4.16)

0.287

No nodal metastasis

4.10 (2.11–7.97)

< 0.001*

No nodal metastasis

5.40 (2.24–14.02)

< 0.001*

Unifocal mass

4.03 (1.80–9.04)

< 0.001*

Unifocal mass

2.36 (0.91–6.08)

0.076

Luminal B subtype

Nodal metastasis

9.54 (3.11–29.30)

< 0.001*

Nodal metastasis

2.54 (0.91–7.09)

0.075

Irregular shape

3.65 (1.38–9.65)

0.006*

Irregular shape

8.04 (2.58–25.07)

< 0.001*

HER2 subtype

Nodal metastasis

5.43 (2.04–14.41)

< 0.001*

Nodal metastasis

4.17 (1.42–12.29)

0.010*

Unifocal mass

5.35 (2.20–13.00)

< 0.001*

Unifocal mass

2.90 (1.04–8.14)

0.043*

Abrupt interface

5.09 (1.92–13.52)

< 0.001*

Abrupt interface

2.73 (0.87–8.53)

0.084

Posterior enhancement or no posterior change

5.03 (1.64–15.38)

0.002*

Posterior enhancement or no posterior change

3.45 (0.95–12.55)

0.060

Calcification

3.06 (1.29–7.28)

0.009*

Calcification

2.76 (1.02–7.46)

0.045*

TN subtype

Circumscribed or lobulated margin

23.73 (5.37–104.93)

< 0.001*

Circumscribed or lobulated margin

8.21 (1.41–47.83)

0.019*

Oval or rounded shape

18.92 (4.29–83.44)

< 0.001*

Oval or rounded shape

6.90 (1.29–36.83)

0.024*

Posterior enhancement or no posterior change

11.65 (2.65–51.25)

< 0.001*

Posterior enhancement or no posterior change

3.67 (0.60–22.51)

0.160

Abrupt interface

8.95 (2.92–27.46)

< 0.001*

Abrupt interface

1.38 (0.28–6.68)

0.691

Parallel orientation

3.56(1.42–8.96)

0.005*

Parallel orientation

2.01 (0.61–6.59)

0.251

No nodal metastasis

3.14 (1.19–8.31)

0.017*

No nodal metastasis

2.09 (0.62–7.03)

0.233

  1. Predictive SS sonographic signs
  2. *Result with statistically significant difference P < 0.05