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Table 2 Number of detected lesions in all patients in different brain regions by each used sequence and relative comparison of 3D-FLAIR versus 2D-FLAIR and T2 pulse sequences

From: Diagnostic value of 3D-FLAIR magnetic resonance sequence in detection of white matter brain lesions in multiple sclerosis

Regions

 

Relative comparison (%)b

3D-FLAIRa

2D-FLAIRa

T2a

3D-FLAIR/2D-FLAIR

P value c

3D-FLAIR/T2

P value c

Supra-tentorial

Periventricular

107

83

76

29

0.001*

41

0.001*

Deep white matter

112

92

86

22

0.005*

30

0.002*

Juxta-cortical

42

15

17

180

< 0.001*

147

0.001*

Infratentorial

9

5

8

80

0.28

13

0.76

Total

270

195

187

38

< 0.001*

44

<0.001*

  1. aData are numbers of detected lesions
  2. bData are relative differences in the numbers of detected lesions expressed as percentages of lesion numbers identified with 3D-FLAIR imaging compared with the corresponding 2D-FLAIR and T2 imaging
  3. cp value was obtained from Wilcoxon analysis for matched pairs indicating that more or fewer patients showed higher lesion load measurement with 3D-FLAIR imaging in comparison with the corresponding 2D-FLAIR or T2 imaging
  4. *Significance <0 .05