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Table 5 Comparison between mean liver ADC and normalized liver ADC regarding the diagnostic performance and cutoff values

From: Diffusion-weighted MRI in staging of post hepatitis C fibrosis: does ADC value challenge liver biopsy?

Class Cutoff AUC Sensitivity Specificity PPV NPV Accuracy
Mean liver ADC
F0 vs ≥ F1 1531.0 0.987 96.6 87.4 89 96 92
≤ F1 vs ≥ F2 1409.75 0.968 92.8 85.6 83 94 89
≤ F2 vs ≥ F3 1192.25 0.879 88.1 80.6 61 95 83
≤ F3 vs F4 1093.0 0.940 87.0 85.4 40 98 86
Normalized liver ADC
F0 vs ≥ F1 1.844 0.957 94.9 80.2 84 94 88
≤ F1 vs ≥ F2 1.705 0.973 96.9 87.1 85 97 87
≤ F2 vs ≥ F3 1.499 0.933 88.1 85.9 68 95 86
≤ F3 vs F4 1.355 0.986 95.7 89.3 50 99 90