Diffusion-weighted MRI in staging of post hepatitis C fibrosis: does ADC value challenge liver biopsy?

Egyptian Journal of Radiology and Nuclear Medicine

Table 5 Comparison between mean liver ADC and normalized liver ADC regarding the diagnostic performance and cutoff values

Class	Cutoff	AUC	Sensitivity	Specificity	PPV	NPV	Accuracy
Mean liver ADC
F0 vs ≥ F1	1531.0	0.987	96.6	87.4	89	96	92
≤ F1 vs ≥ F2	1409.75	0.968	92.8	85.6	83	94	89
≤ F2 vs ≥ F3	1192.25	0.879	88.1	80.6	61	95	83
≤ F3 vs F4	1093.0	0.940	87.0	85.4	40	98	86
Normalized liver ADC
F0 vs ≥ F1	1.844	0.957	94.9	80.2	84	94	88
≤ F1 vs ≥ F2	1.705	0.973	96.9	87.1	85	97	87
≤ F2 vs ≥ F3	1.499	0.933	88.1	85.9	68	95	86
≤ F3 vs F4	1.355	0.986	95.7	89.3	50	99	90