Table 7 Sensitivity, specificity, PPV, NPV, and accuracy of PET/CT and BMB
From: PET/CT and bone marrow biopsy (BMB) in evaluating bone marrow in lymphoma
| Â | Â | Sensitivity 95% CI | Specificity 95% CI | PPV 95% CI | NPV 95% CI | Accuracy 95% CI |
|---|---|---|---|---|---|---|
Whole study | PETCT | 95.6 (89.3-100) | 98 (95.2-100) | 95.6 (89.3-100) | 98 (95.2-100) | 97.2 (94.5-99.9) |
BMB | 46.7 (31.5-61.8) | 100 | 100 | 80.6 (73.6-87.7) | 83.4 (77.3-89.6) | |
HD | PETCT | 94.1 (81.6-100) | 97.2 (93.2-100) | 88.9 (72.8-100) | 98.6 (95.7-100) | 96.6 (92.7-100) |
BMB | 35.3 (10-60.6) | 100 | 100 | 86.6 (79.1-94.1) | 87.5 (80.5-94.5) | |
NHL | PETCT | 96.4 (89.1-100) | 100 | 100 | 96.7 (89.8-100) | 98.2 (94.7-100) |
BMB | 53.6 (33.9-73.3) | 100 | 100 | 69.0 (54.5-83.6) | 77.2 (66.0-88.4) | |
Nodular sclerosis | PETCT | 88.9 (63.3-100) | 95 (87.9-100) | 80 (49.8-100) | 97.4 (92.2-100) | 93.9 (86.9-100) |
BMB | 33.3 (0.0-71.8) | 100 | 100 | 87.0 (76.8-97.1) | 87.8 (78.2-97.3) | |
Mixed cellularity | PETCT | 100 | 100 | 100 | 100 | 100 |
BMB | 42.9 (0.0-92.3) | 100 | 100 | 82.6 (65.8-99.4) | 84.6 (69.8-99.5) | |
DLBCL | PETCT | 100 | 100 | 100 | 100 | 100 |
BMB | 53.3 (24.7-81.9) | 100 | 100 | 63.2 (39.3-87.0) | 74.1 (56.4-91.7) |