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Egyptian Journal of Radiology and Nuclear Medicine
Fig. 3 | Egyptian Journal of Radiology and Nuclear Medicine

Fig. 3

From: Diffusion-weighted magnetic resonance imaging (DWMRI) of head and neck squamous cell carcinoma: could it be an imaging biomarker for prediction of response to chemoradiation therapy

Fig. 3

A 28-years-old female patient with stage III nasopharyngeal SCC (T1N2M0) treated by concomitant chemoradiotherapy. a–e axial pretreatment MR images. a T2WI with fat suppression, b non-contrast T1WI, c post-GAD T1WI with fat suppression, d b-1000 TSE-DWI, e the corresponding ADC map, all showed mainly left-sided nasopharyngeal soft tissue mass with restricted diffusion (ADC = 0.7 × 10−3 mm2/s), f–h axial midtreatment MR images performed 2 weeks after start of chemoradiotherapy. f T2WI with fat suppression, g b-1000 TSE-DWI, h the corresponding ADC map, all showed mild regression of tumor size with elevation of ADC value (1.3 × 10−3 mm2/s). i–k Axial MR images 6 weeks after end of CRT, i T2WI with fat suppression, j b-1000 TSE-DWI, k the corresponding ADC map, revealed complete disappearance of the tumor leaving thin smooth nasopharyngeal mucosa, yet showing restricted diffusion (ADC = 0.97 × 10−3 mm2/s) so residual tumor was still suspected. l Axial T2WI with fat suppression 1.5 years after end of treatment showed stationary appearance with no development of any new mass confirming local control of the tumor and that it was normal nasopharyngeal lymphoid tissue

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