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Fig. 4 | Egyptian Journal of Radiology and Nuclear Medicine

Fig. 4

From: Diffusion-weighted magnetic resonance imaging (DWMRI) of head and neck squamous cell carcinoma: could it be an imaging biomarker for prediction of response to chemoradiation therapy

Fig. 4

A 39-year-old female patient with stage III hypopharyngeal SCC (T2N1M0) treated by concomitant chemoradiotherapy. a–e Axial pretreatment MR images. a T2WI with fat suppression, b non-contrast T1WI, c post-GAD T1WI with fat suppression, d b-1000 TSE-DWI, e the corresponding ADC map, all showed moderately hyperenhancing T2 hyperintense hypopharyngeal soft tissue mass involving the right pyriform sinus and postcricoid region, DWI shows high ADC (1.42 × 10−3 mm2/s). f–h Axial midtreatment MR images performed 3 weeks after start of chemoradiotherapy. f T2WI with fat suppression, g b-1000 TSE-DWI, h the corresponding ADC map, all showed mild progression in size of the tumor with no elevation of ADC value (ADC = 1.37 × 10−3 mm2/s). i Axial post-GAD T1WI with fat suppression 8 weeks after end of CRT revealed no response to treatment with progressive tumor that was proved by endoscopic assessment and biopsy

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