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Fig. 7 | Egyptian Journal of Radiology and Nuclear Medicine

Fig. 7

From: Arterial spin-labelling and magnetic resonance spectroscopy as imaging biomarkers for detection of epileptogenic zone in non-lesional focal impaired awareness epilepsy

Fig. 7

ad The ROC curves analysis illustrates the performance of quantitative parameters of PASL-MRI and 1H-MRS techniques in identification of the zone of epileptogenic activity in the studied patients. The rCBF at a cut-off value ≤ 64.87 ml/100 g/min with 0.957 AUC showed 98.31% sensitivity, 92.90% specificity and 94.75% accuracy and by using the ASLAI% at a cut-off value ≥ 5.96 with 0.968 AUC, yielded 96.01% sensitivity, 91.70% specificity and 95.78% accuracy (a and b, respectively). Moreover, c revealed that NAA/Cho ratio at a cut-off value ≤ 0.78 with 0.949 AUC, gave 93.0% sensitivity, 91.7% specificity and 93.94% accuracy, while NAA/Cr ratio at a cut-off value ≤ 0.89 with 0.889 AUC showed 89.3% sensitivity, 88.2% specificity and 88.9% accuracy. On the other hand, NAA/(Cho + Cr) ratio at a cut-off value ≤ 0.59 with 0.977 AUC, yielded 100% sensitivity, 96.9% specificity and 97.74%. Also, MI/NAA ratio at a cut-off value ≥ 0.98 with 0.989 AUC, yielded 100% sensitivity 96.34% specificity and 97.86% accuracy, while Glx/NAA ratio at a cut-off value ≥ 1.55 with 0.972 AUC, yielded 100% sensitivity, 96.35% specificity and 97.24% accuracy, while Glx/Cr ratio at a cut-off value ≥ 1.39 with 0.955 AUC, showed 92.06% sensitivity, 90.24% specificity and 94.53% accuracy. Furthermore, utilization of %AF at a cut-off value ≥ 9.98 with 0.983 AUC, gave 100% sensitivity, 97.65% specificity and 98.14% accuracy (d)

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