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Table 6 The %AF of the mean metabolites concentration ratio obtained by multivoxel 1H-MRS in the studied patients (n = 26)

From: Arterial spin-labelling and magnetic resonance spectroscopy as imaging biomarkers for detection of epileptogenic zone in non-lesional focal impaired awareness epilepsy

Laterality of the epileptogenic activity as obtained by 1H-MRS data The %AF of the mean metabolites ratios
NAA/Cho NAA/Cr NAA/(Cho + Cr) MI/NAA Glx/NAA Glx/Cr
Trivial %AF with no lateralization (1/26; 3.85%) 4.2 3.5 3.3 4 3 4
%AF with lateralization (25/26; 96.15% Right lateralization (12; 46.15%) − 1.5–37.5 (25.2 ± 2.2) − 1.5–30 (24.6 ± 5) − 1.5–29.8 (27.4 ± 1.7) − 1.49–24 (20.5 ± 2.3) − 1.2–30.6 (20.0 ± 1.8) − 1.1–38.9 (25.1 ± 13)
Left lateralization (13; 50%) 15–37 (26.0 ± 1.1) 12–31.4 (25.1 ± 4.4) 12–30.2 (29.1 ± 1.5) 10.5–35.7 (22.0 ± 12) 13.9–30.5 (21.5 ± 11) 12–30.01 (26.2 ± 12)
ANOVA F 66.44 149.613 27.87 39.41 1.462 1.104
P value < 0.001* < 0.002* < 0.001* < 0.01* 0.02* 0.03*
  1. MV 1H-MRS multi-voxel proton magnetic resonance spectroscopy, ppm parts per million, NAA N-acetylaspartate, Cr creatine, Cho choline, Glx glutamate-glutamine, MI Myo-inositol, %AF percent asymmetry factor; statistical data were expressed as number (n); percent (%), mean ± standard deviation (SD) and F Fisher exact test, *: significant if P value ˂ 0.05