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Table 6 The %AF of the mean metabolites concentration ratio obtained by multivoxel 1H-MRS in the studied patients (n = 26)

From: Arterial spin-labelling and magnetic resonance spectroscopy as imaging biomarkers for detection of epileptogenic zone in non-lesional focal impaired awareness epilepsy

Laterality of the epileptogenic activity as obtained by 1H-MRS data

The %AF of the mean metabolites ratios

NAA/Cho

NAA/Cr

NAA/(Cho + Cr)

MI/NAA

Glx/NAA

Glx/Cr

Trivial %AF with no lateralization (1/26; 3.85%)

4.2

3.5

3.3

4

3

4

%AF with lateralization (25/26; 96.15%

Right lateralization (12; 46.15%)

− 1.5–37.5 (25.2 ± 2.2)

− 1.5–30 (24.6 ± 5)

− 1.5–29.8 (27.4 ± 1.7)

− 1.49–24 (20.5 ± 2.3)

− 1.2–30.6 (20.0 ± 1.8)

− 1.1–38.9 (25.1 ± 13)

Left lateralization (13; 50%)

15–37 (26.0 ± 1.1)

12–31.4 (25.1 ± 4.4)

12–30.2 (29.1 ± 1.5)

10.5–35.7 (22.0 ± 12)

13.9–30.5 (21.5 ± 11)

12–30.01 (26.2 ± 12)

ANOVA

F

66.44

149.613

27.87

39.41

1.462

1.104

P value

< 0.001*

< 0.002*

< 0.001*

< 0.01*

0.02*

0.03*

  1. MV 1H-MRS multi-voxel proton magnetic resonance spectroscopy, ppm parts per million, NAA N-acetylaspartate, Cr creatine, Cho choline, Glx glutamate-glutamine, MI Myo-inositol, %AF percent asymmetry factor; statistical data were expressed as number (n); percent (%), mean ± standard deviation (SD) and F Fisher exact test, *: significant if P value ˂ 0.05