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Table 3 TMN staging for upper tract urothelial cancer [24]

From: Multimodality imaging review of focal renal lesions

TNM stage Disease extent
Ta Noninvasive papillary carcinoma
Tis Carcinoma in situ
T1 Invasion of subepithelial connective tissue/lamina propria
T2 Invasion of muscularis propria
T3 Invasion of renal parenchyma
T4 Invasion of adjacent organs, the pelvic or abdominal wall or through the parenchyma into the perinephric fat
N0 No regional lymph node metastases
N1 Metastasis to a single node < 2 cm in greatest dimension
N2 Metastasis to a single node 2–5 cm in greatest dimension or multiple nodes < 5 cm in greatest dimension
N3 Metastasis to a node > 5 cm in greatest dimension
M0 No distant metastasis
M1 Distant metastases