Table 3 TMN staging for upper tract urothelial cancer [24]
TNM stage | Disease extent |
|---|---|
Ta | Noninvasive papillary carcinoma |
Tis | Carcinoma in situ |
T1 | Invasion of subepithelial connective tissue/lamina propria |
T2 | Invasion of muscularis propria |
T3 | Invasion of renal parenchyma |
T4 | Invasion of adjacent organs, the pelvic or abdominal wall or through the parenchyma into the perinephric fat |
N0 | No regional lymph node metastases |
N1 | Metastasis to a single node < 2 cm in greatest dimension |
N2 | Metastasis to a single node 2–5 cm in greatest dimension or multiple nodes < 5 cm in greatest dimension |
N3 | Metastasis to a node > 5 cm in greatest dimension |
M0 | No distant metastasis |
M1 | Distant metastases |