Fig. 3
From: The role of diffusion-weighted MRI in assessment of response to chemotherapy in osteosarcoma
A 7-year-old female with osteosarcoma in the left femur. MR images a–c before and d–f after chemotherapy. a, b Axial T2-WI and post contrast-enhanced T1-WI showing left femur intra medullary infiltrative lesion with circumferential soft tissue mass eliciting heterogeneous mixed signal in T2 and heterogeneous contrast uptake. c ADC map showed diffusion restriction with mean ADC values of the most restricted ROIs about (mean, 1.1 × 10−3 mm2/s). d, e Follow-up axial T2-WI and contrast-enhanced T1-WI showing minimal size regression with heterogeneous enhancement. f Follow-up ADC map showing elevated ADC values (mean, 2.30 × 10−3 mm2/s) denoting good therapeutic response