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Fig. 5 | Egyptian Journal of Radiology and Nuclear Medicine

Fig. 5

From: The role of diffusion-weighted MRI in assessment of response to chemotherapy in osteosarcoma

Fig. 5

A 18-year-old male with osteosarcoma in the right humerus. MR images ac before and df after chemotherapy. a, b Axial T2-WI and contrast-enhanced T1-WI showing cortically based meta-diaphyseal mass lesion circumferentially surrounding the right humerus infiltrating its medulla all over the shaft. It elicits heterogeneous high signal in T2 with heterogeneous contrast uptake. c ADC map showed diffusion restriction with mean ADC values of the most restricted ROIs about (mean, 1.29 × 10−3 mm2/s). d, e Follow-up conventional axial T2 and post contrast showing size progression and more contrast enhancement. f Follow-up ADC mapping showed no significant interval changes (1.3 × 10−3 mm2/s) indicating poor response

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