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Fig. 5 | Egyptian Journal of Radiology and Nuclear Medicine

Fig. 5

From: Cerebellum and brain stem volume loss in relapsing remission multiple sclerosis by MRI volumetry: relation to neurological disability score and number of relapses

Fig. 5

A 25-year-old female patient aged 25 years old with RRMS, EDSS score of 0.5, and a relapse rate of 1, complaining of pyramidal dysfunction. Axial and sagittal Flair sequences (a–c) showed multiple plaques of high SI seen at both parietal lobes; in periventricular white matter, pericallosal areas right deep white matter (basal ganglia). 3D T1W images in sagittal view (d, e) for brain stem segmentation and in coronal view (f, g) for cerebellar grey and white matter segmentation; (d, f) raw unprocessed T1W image, (e, g) 3D T1image after processing with 3D Slicer with colored segmented brain stem and cerebellum structures. The brain stem and cerebellum segmentation results showed the following data: midbrain 5.9 (N 5.24–6.33 cm3), pons 13.85 (N 12.66–16.51 cm3), medulla 3.63 (N 4.25–5.12 cm3), whole brain stem was 23.38 (N 22.46–28.10 cm3), left cerebellar white matter 24 (N 19.06–25.21 cm3), left cerebellar grey matter 84.59 (N 84.39–102.17 cm3), right cerebellar white matter 23.7 (N 18.55–25.54 cm3), and right cerebellar grey matter 84.5 (N 84.36–101.87 cm3). Patient with EDSS score of 0.5 and a relapse rate of 1 had a mild decrease in the volume of the medulla oblongata only

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