Fig. 1

Cross-sectional measurements at the site of the maximal plaque burden at the point of the lesion marked red. a. Plaque components; area represented the area of all pixels on the cross-section corresponding to the plaque component. Average HU; the mean value of the intensity of the pixels on the cross-section corresponding to the plaque component. Standard deviation; the standard deviation of the intensity of the pixels on cross-section corresponding to the plaque component. Volume measurements of the whole plaque at highlighted blue marks. b Calculated for each defined lesion; remodeling index and plaque components; remodeling index is the ratio of the vessel area at the point of the lesion marked red to the proximal reference area marked green