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Table 3 SUVmax and TMA of activated BAT according to patients and tumor characteristics

From: Brown adipose tissue (BAT) activation at 18F-FDG PET/CT: correlation with clinicopathological characteristics in breast cancer

Parameter

BAT SUVmax

BAT TMA

Mean ±SD

P value

Mean ± SD

P value

Age:

0.597a

< 50 years

13.7 ±10

0.683a

81.9 ± 47.8

≥ 50 years

10.5 ±10.6

63 ± 15.5

Disease stage:

0.883a

I & II

10 ±9.9

0.148a

81 .1 ± 54

III & IV

17 ±8.8

77.5 ± 34.6

Histology:

0.256b

IDC

13.2 ±10.4

0.978b

74.5 ± 33.8

ILC

13.5 ± 7.7

114.5 ± 13.8

Grade

0.521b

I

18.5±20.5

0.756b

92 ± 14

II

12.4± 8.5

87.8 ± 51.6

III

12.8 ± 10

59.6 ± 39.2

Molecular subtypes

=0.272b

Luminal A

17±13.4

0.272b

72.4 ± 21.2

Luminal B

10 ±5.7

92.5 ± 55.5

Basal-like

9.3 ±8.7

43.3 ± 32.5

HER2+ve

28 ± 0

133 ± 0

ER receptor status

0.831a

Positive

13.5 ± 10

0.936a

81.3 ± 45

Negative

13 ±10

75.8 ± 50.4

PR receptor status

0.951a

Positive

14.5±10

0.554a

79 ± 47

Negative

11.3 ± 10

80 ± 46.5

Her2-receptor status

0.019a

Positive

11.6 ± 10

0.657a

117.2± 56.4

Negative

14 ± 10.4

62.5 ± 27.5

Ki-level

0.552b

<14

33 ± 0

0.112b

102 ± 0

≥14

11.4 ± 6

89.3 ± 52.2

Not assessed

12.7± 11

65.3 ± 38.4

N-stage:

0.626a

N0

13 ± 12.9

0.936a

71 ± 25.1

N1-3 (mean)

13.5 ±12

83.5 ± 52.5

M-stage

0.868a

M0

24.6 ± 4.9

0.021a

78.6 ± 47.3

M1

10.6 ± 8.8

83.7 ± 43.3

  1. aIndependent sample T test, bOne-way ANOVA
  2. SUVmax maximum standardized uptake value, TMA total metabolic activity