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Table 1 Characteristics of HSCT patients

From: Patterns of central nervous system complications of post-hematopoietic stem cell transplant in pediatric oncology patients: a single institute experience

 

Total cases

AutoSCT

AlloSCT

Age (in years)

Mean

8.2

7.6

9.1

Median

6.5

6

8.3

Standard deviation

5.2

5.1

5.2

Minimum

0.9

1

0.9

Maximum

25

25

19.3

Sex

Female

190

114

76

Male

335

197

138

Initial diagnosis

No (%)

No (%)

No (%)

Neuroblastoma (NB)

210 (40%)

208 (66.9%)

2 (0.9%)

  CR

148

1

  Othersa

60

1

Non-Hodgkin lymphoma (NHL)

21 (4%)

11 (3.5%)

10 (4.7%)

  1st CR

2

1

  2nd CR

9

9

Acute myeloid leukemia (AML)

76 (14.5%)

2 (0.6%)

74 (34.6%)

  1st CR

1

43

  2nd CR

1

31

Acute lymphoblastic leukemia (ALL)

44 (8.2%)

1 (0.32%)

43 (20.1%)

  1st CR

 

0

26

  2nd CR

1

17

Myelodysplastic/myeloproliferative syndrome

80 (15.2%)

0 (0%)

80 (37.3%)

Hemophagocytic lymphohistocytosis (HLH)

5 (1%)

0 (0%)

5 (2.3%)

Hodgkin lymphoma (HL)

77 (14.7%)

77 (24.8%)

0 (0%)

  Refractory

63

  Relapsing

14

Relapsing Wilms’s

2 (0.4%)

2 (0.6%)

0 (0%)

  Extraocular retinoblastoma (RB)

10 (1.9%)

10 (3.2%)

0 (0%)

Total

525 (100%)

311 (100%)

214 (100%)

  1. aOthers contain very good PR and PR neuroblastoma patients
  2. CR Complete response, PR Partial response