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Table 9 Showing a comparison of diagnostic performance of TI-RADS alone, SWE alone, color Doppler alone, and the combined parallel method

From: Conventional ultrasound, color Doppler, TI-RADS, and shear wave elastography for thyroid nodule differentiation: a study of efficacy compared with the histopathology results

Imaging method

 

Malignant

Benign

AUC%

Sensitivity

Specificity

PLR

NLR

PPV

NPV

TI-RADS alone (4 as a cutoff value)

+

28

11

84 (75.4–90.7)

84.8

83.3

5.09

0.182

71.7

91.6

5

55

Color Doppler alone (1b as a cutoff value)

+

18

0

77 (67.8–85.1)

54.5

100

 

0.45

100

81.4

15

66

SWE alone (ER 2.6 as a cutoff value)

+

30

7

96 (93.3–99.4)

90.9

89.3

8.5

0.10

81.08

95.1

3

59

SWE alone (Emean 34.3 as cutoff value)

+

28

11

84 (75.4–90.7)

84.8

83.3

5.09

0.182

71.7

91.6

5

55

Combined TIRADS & color Doppler

 

29

11

85 (77.1–91.9)

87.8

83.3

5.2

0.145

72.5

93.2

 

4

55

Combined TIRADS + SWE (ER)

+

30

17

#

90.9

74.2

3.5

0.12

63.8

94.2

3

49

Combined TIRADS + SWE (Emean)

+

30

21

#

90.9

68.1

2.8

0.133

58.8

93.7

3

45

  1. AUC, areas under the ROC curve; PLR, positive likelihood ratio; NLR, negative likelihood ratio; PPV, positive predictive value; NPV, negative predictive value; 95% CI, 95% confidence interval
  2. + stands for positivity for malignancy, − stands for negativity for malignancy, # stands for not applicable