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Table 5 Summary of the statistical results regarding “step 2 blinded validation analysis”

From: COVID-19 clinico-radiological mismatch: a proposal for a novel combined morphologic/volumetric CT severity score with blinded validation

 

Mild CTSI

Moderate CTSI

Severe CTSI

 

Mild clinical disease

86 (91%)

6

2 (with patchy crazy-paving and early fibrosis)

Total (disease) = 94

Borderline severe clinical disease

1

14 (82%)

2 (with patchy crazy-paving and early fibrosis)

Total (disease) = 17

Severe or critical disease

4

3

14 (67%)

Total (disease) = 21

Total (CT)

91 (69%)

23 (17%)

18 (14%)

Total = 132

Prevalence

71.2%

12.9%

15.9%

 

Sensitivity

91.5%

82.4%

66.7%

Mean = 80.2%

Specificity

86.8%

92.2%

96.4%

Mean = 91.8%

PPV (positive predictive value)

94.5%

60.9%

77.8%

Mean = 77.7%

NPV (negative predictive value)

80.5%

97.2%

93.9%

Mean = 90.5%

IOA (inter-observer agreement)

87.5%

81.3%

100%

Mean = 89.6%

AUC (area under curve)

0.9003

0.83007

0.7765

Mean = 0.8356

Confidence interval

0.832

0.748

0.684

Mean = 0.7546

Accuracy

90.1%

90.9%

91.7%

Mean = 90.9%

Validity of the test

Excellent

Good

Fair