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Table 2 Association between sonographic characteristics and cytology results of the thyroid nodules with microcalcification

From: Can sonographic features of microcalcification predict thyroid nodule malignancy? a prospective observational study

Sonographic features

Benign (n [%])

Malignant (n [%])

P-value

Odds ratio (95% confidence interval)

Nodule size (cm)

< 2

85 (73.3)

31 (26.7)

 

1

≥ 2

17 (85)

3 (15)

0.263

0.484 (0.133–1.766)

Microcalcification number

<5

81 (81)

19 (19)

 

1

>5

21 (58.3)

15 (41.7)

0.007

3.045 (1.328–6.982)

Echogenicity

Hyperechogenicity

23 (88.5)

3 (11.5)

 

1

Isoechogenicity

37 (78.7)

10 (21.3)

0.305

2.072 (0.515–8.329)

Hypoechogenicity

42 (66.7)

21 (33.3)

0.045

3.833 (1.032–14.238)

Composition

Solid-cystic

29 (76.3)

9 (23.7)

 

1

Solid

73 (74.5)

25 (25.5)

0.825

0.906 (0.378–2.174)

Margin

Regular

63 (85.1)

11 (14.9)

 

1

Irregular

12 (63.2)

7 (36.8)

0.037

3.341 (1.078–10.352)

Ill defined

17 (73.9)

6 (26.1)

0.222

2.021 (0.653–6.256)

Lobulated

10 (50)

10 (50)

0.002

5.727 (1.934–16.959)