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Table 3 Diagnostic performances of tumor-nipple enhancement, abnormal nipple morphology, symmetry of nipple morphology, abnormal nipple enhancement and tumor-nipple distance in prediction of NAC invasion by underlying breast cancer

From: Prediction of nipple-areolar complex involvement by breast cancer: role of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI)

  Sensitivity
(%)
Specificity
(%)
PPV
(%)
NPV
(%)
Accuracy
(%)
Abnormal nipple enhancement 57.6 97.8 90.5 86.5 87.2
Abnormal nipple morphology 63.6 93.4 77.7 87.7 85.6
Symmetry of nipple morphology 63.6 96.7 87.5 88.1 88
TNE (tumor nipple enhancement) 72.7 76.1 52.2 88.6 75.2
TND/cm
≤ 2 cm
63.6 72.8 45.7 84.8 54.4
  1. NPV negative predictive value, PPV positive predictive value