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Table 4 Comparison of diagnostic performance for transition zone prostate cancer detection between PI-RADS v2.1 and PI-RADS v2.1-B

From: In prostatic transition zone lesions (PI-RADS v2.1): which subgroup should be biopsied?

 

Reader 1

Reader 2

PI-RADS

P value

PI-RADS

P value

v 2.1

v 2.1-B

v 2.1

v 2.1-B

Sensitivity

100 (91/91)

97.8 (89/91)

0.155

100 (91/91)

96.7 (88/91)

0.081

Specificity

38.1 (24/63)

93.7 (59/63)

< 0.000

17.0 (8/47)

90.5 (57/63)

< 0.000

Positive predictive value

70.0 (91/130)

95.7 (89/93)

< 0.000

70.0 (91/130)

93.6 (88/94)

< 0.000

Negative predictive value

100 (24/24)

96.7 (59/61)

0.369

100 (8/8)

95.0 (57/60)

0.518

AUC

0.933 (0.896-0.971)

0.972 (0.946-0.998)

 

0.926 (0.896–0.965)

0.960 (0.929–0.991)

 
  1. AUC area under the receiver operating characteristic curve