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Table 1 Determinants of the primary Lesion SUVmax among cases

From: Correlation of primary tumor metabolic parameters with clinical, histopathological and molecular characteristics in breast cancer patients at pre-operative staging FDG-PET/CT study

 

Lesion SUVmax

P-value

Mean ± SD

Median (IQR)

Pathology

   

• IDC(n=36)

3.96±3.1

2.85(3.33)

=0.258#

• ILC(n=3)

2.41±2.98

0.8

• Other (n=1)

1

 

Menopausal State

   

• Pre- (n=19)

14.55 ± 2.1

13 (6)

0.003*

• Post- (n=21)

7.45 ± 1.0

7 (2)

Disease Stage

   

• I & II (n=27)

8.79 ± 1.1

7 (2)

= 0.017*

• III & IV (n=13)

15.06 ± 2.9

14 (5)

ER-Receptors

   

Positive (n=31)

9.12 ± 5.7

7 (6)

= 0.010**

Negative (n=9)

16.70 ± 9.6

12.5 (11)

PR-Receptors

   

Positive (n=24)

9.13 ± 6.2

7 (5)

= 0.113**

Negative (n=16)

13.37 ± 9.7

9 (8.5)

Her2-neu Receptors

   

Positive (n=14)

12.35 ± 5.8

13 (9.5)

=0.089**

Negative (n=26)

10.01 ± 8.9

7 (6.5)

Tumor grad

GI (n=5)

3.69±1.4

3.1(2.6)

 

GII (n=18)

9.43±6.11

6.85(11.08)

=0.002#

GIII (n=15)

15.03±9.20

11.11(13.4)

 

Molecular subtype

   

Luminal A (n=10)

5.88±4.9

4.18(5.06)

0.007#

Luminal B (n=19)

10.93±5.55

8.4(9)

Her2neu over expression (n=4)

8.03±5.24

7.98(9.13)

Triple negative (n=7)

19.19±11.86

21.6(17.67)

Axillary LN State

Positive (n=27)

12.80 ± 8.6

10 (8.5)

= 0.016**

Negative(n=13)

6.73 ± 4.1

6.5 (6)

  1. *Independent t-test
  2. **Mann Whitney U
  3. # Kruskal Wallis test