Category descriptor | Category malignancy | Probability management | Recommendation |
---|---|---|---|
Negative | 1 | < 1% | Continue annual screening with LDCT in 12 months |
Benign appearance or behavior | 2 | < 1% | Continue annual screening with LDCT in 12 months |
Probably benign | 3 | 1–2% | 6-month LDCT |
Suspicious | 4A | 5–15% | 3-month LDCT; PET/CT may be used when there is a ≥ 8 mm solid component |
4B 4X | > 15% | Chest CT with/without contrast, PET/CT, and/or tissue sample that depends on the probability of malignancy and comorbidities. PET-CT may be used when there is a ≥ 8-mm solid component |