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Table 1 Clinical and radiological findings of 20 patients with breast involvement of hematological malignancies

From: Breast involvement of hematological malignancies: imaging and clinical findings

Case Age Pathologic type Primary/secondary lymphoma Size (mm) Sidea Axillary LAP/skin thickening MMG US MRI
1 83 Diffuse large B-cell lymphoma Primary 36 Lefta +/+ NA Irregular/non-circumscribed
Hypoechoic
Posterior enhancement
Vascularity: NA
NA
2 57 Diffuse large B-cell lymphoma Primary 11 Right +/+ Oval-round
Circumscribed
Isodense
Oval-round/non-circumscribed
Hypoechoic
Posterior enhancement
Hypervascularity
NA
3 37 Diffuse large B-cell lymphoma Secondary 13 Bilateral +/+ Asymmetric density
Isodense
Irregular/non-circumscribed
Hypoechoic
Posterior phenomena: −
Vascularity: NA
NA
4 47 Diffuse large B-cell lymphoma Secondary 160 Left +/+ NA Irregular/non-circumscribed
Heterogeneous
Posterior phenomena: −
Vascularity: NA
NA
5 57 Diffuse large B-cell lymphoma Secondary 47 Righta +/− Asymmetric density
Hyperdense
Oval-round/non-circumscribed
Heterogeneous c
Posterior enhancement
Vascularity: NA
Dynamic curve, 2
Diffusion restriction (ADC 0.542 × 10−3)
T2-hyperintense
6 67 Diffuse large B-cell lymphoma Primary 81 Righta −/+ NA Oval-round/circumscribed
Heterogeneous c
Posterior enhancement
Vascularity: NA
NA
7 65 Diffuse large B-cell lymphoma Secondary 22 Bilateral +/+ Oval-round
Circumscribed
Hyperdense
Oval-round/circumscribed
Hypoechoic
Posterior phenomena: −
Hypervascularity
NA
8 62 Marginal zone lymphoma Secondary 30 Lefta −/− Oval-round
Circumscribed
Isodense
Oval-round/circumscribed
Heterogeneous c
Posterior enhancement
Hypervascularity
NA
9 69 Marginal zone lymphoma Secondary 14 Bilateral +/− Oval-round
Circumscribed
Hyperdense
Oval-round/circumscribed
Hypoechoic
Posterior enhancement
Hypervascularity
NA
10 77 Marginal zone lymphoma Secondary 54 Lefta +/− NA Irregular/non-circumscribed
Heterogeneous
Posterior enhancement
Vascularity: NA
NA
11 48 Marginal zone lymphoma Primary 13 Righta +/+ NA Irregular/non-circumscribed
Hypoechoic
Posterior enhancement
Hypervascularity
NA
12 55 Marginal zone lymphoma Secondary 32 Left +/− Irregular
Non-circumscribed
Hyperdense
Irregular/non-circumscribed
Hypoechoic
Posterior enhancement
Vascularity: NA
Dynamic curve, 2
Diffusion restriction (ADC 0.558 × 10−3)
T2-hyperintense
13 19 Granulocytic sarcoma Primary 35 Left −/− NA Oval-round/circumscribed
Heterogeneous c
Posterior enhancement
Hypervascularity
NA
14 50 Granulocytic sarcoma Secondary 25 Left −/+ NA Irregular/non-circumscribed
Heterogeneous c
Posterior enhancement
Vascularity: NA
NA
15d 22 Granulocytic sarcoma Secondary 47 Bilateral +/+ b Oval-round
Circumscribed
Hyperdense
Oval-round Circumscribed
Heterogeneous c
Posterior enhancement
Vascularity: NA
Dynamiccurve, 3
Diffusion restriction (ADC 0.403 × 10−3)
T2-hyperintense
16 21 Hodgkin lymphoma Secondary 40 Bilateral +/+ NA Irregular/non-circumscribed
Heterogeneous c
Posterior phenomena: −
Vascularity: NA
NA
17 36 Hodgkin lymphoma Secondary 60 Right −/+ Irregular
Non-circumscribed
Hyperdense
Irregular/non-circumscribed
Heterogeneous
Posterior enhancement
Hypervascularity
NA
18 22 Precursor B lymphoblastic lymphoma Secondary 42 Righta −/− NA Irregular/non-circumscribed
Heterogeneous
Posterior enhancement
Hypervascularity
NA
19 36 Mycosis fungoides Secondary 46 Righta +/+b NA Irregular/non-circumscribed
Heterogeneous
Posterior phenomena: −
Hypervascularity
NA
20 58 Plasmacytoma Secondary 9 Righta +/− Oval-round
Circumscribed
Hyperdense
Oval-round/Circumscribed
Hypoechoic
Vertical orientation
Posterior phenomena: −
Hypervascularity
Dynamic curve, 2
Diffusion restriction (ADC 0.840 × 10−3)
T2-hyperintense
  1. Abbreviations: LAP lymphadenopathy, US ultrasonography, MMG mammography, MRI magnetic resonance imaging, NA not applicable, ADC apparent diffusion coefficient
  2. aShows single lesions within the left or right breast
  3. bSkin thickening is because of invasion by the mass
  4. cHeterogeneity is due to hyperechoic areas
  5. dThis patient has multiple lesions, some of which have an oval-round shape, circumscribed margins, and type 3 dynamic curve, while others show irregular shape, not-circumscribed margin, and type 2 dynamic curve