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Table 7 Diagnostic accuracy of CESM in the whole study cohort versus the result of biopsy or follow-up as the gold standard for lesion classification

From: Contrast-enhanced spectral mammography: successful initial clinical institute experience

Lesion classification by SMG Final diagnosis  
Malignant Benign Total
Probably malignant (BIRADS 4–6) 84 8 92
Probably benign (BIRADS 1–3) 2 29 31
Total 86 37 123
Statistic Value Lower bound (95%) Upper bound (95%)
Correct classification 92% 87% 97%
Misclassification 8% 3% 13%
Sensitivity 98% 91% 100%
Specificity 78% 62% 89%
False positive rate 22% 9% 34%
False negative rate 2% 0% 5%
Prevalence 70% 62% 78%
Positive predictive value (PPV) 91% 86% 97%
Negative predictive value (NPV) 94% 85% 100%
Positive likelihood ratio (LR+) 4.52 2.44 8.35
Negative likelihood ratio (LR−) 0.03 0.01 0.12
Relative risk 14.15 4.30 46.57
Odds ratio 152.25 34.97 662.91
  1. Data in cross-tables are counts