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Table 8 Diagnostic accuracy of CESM tested in patients with ACR grade A/B versus the result of biopsy or follow-up as the gold standard for lesion classification

From: Contrast-enhanced spectral mammography: successful initial clinical institute experience

Lesion classification by SMG Final diagnosis  
Malignant Benign Total
Probably malignant (BIRADS 4–6) 35 3 38
Probably benign (BIRADS 1–3) 1 10 11
Total 36 13 49
Statistic Value Lower bound (95%) Upper bound (95%)
Correct classification 92% 84% 100%
Misclassification 8% 0% 16%
Sensitivity 97% 84% 100%
Specificity 77% 49% 92%
False positive rate 23% 3% 43%
False negative rate 3% 0% 8%
Prevalence 73% 61% 86%
Positive predictive value (PPV) 92% 84% 100%
Negative predictive value (NPV) 91% 74% 100%
Positive likelihood ratio (LR+) 4.21 1.56 11.38
Negative likelihood ratio (LR−) 0.04 0.01 0.26
Relative risk 10.13 2.27 45.19
Odds ratio 116.67 15.28 890.87
  1. Data in cross-tables are counts