Table 9 Diagnostic accuracy of CESM tested in patients with ACR grade C/D versus the result of biopsy or follow-up as the gold standard for lesion classification
From: Contrast-enhanced spectral mammography: successful initial clinical institute experience
Lesion classification by SMG | Final diagnosis | Â | |
|---|---|---|---|
Malignant | Benign | Total | |
Probably malignant (BIRADS 4–6) | 49 | 5 | 54 |
Probably benign (BIRADS 1–3) | 1 | 19 | 20 |
Total | 50 | 24 | 74 |
Statistic | Value | Lower bound (95%) | Upper bound (95%) |
Correct classification | 92% | 86% | 98% |
Misclassification | 8% | 2% | 14% |
Sensitivity | 98% | 88% | 100% |
Specificity | 79% | 59% | 91% |
False positive rate | 21% | 6% | 36% |
False negative rate | 2% | 0% | 6% |
Prevalence | 68% | 57% | 78% |
Positive predictive value (PPV) | 91% | 83% | 98% |
Negative predictive value (NPV) | 95% | 85% | 100% |
Positive likelihood ratio (LR+) | 4.70 | 2.15 | 10.27 |
Negative likelihood ratio (LR−) | 0.03 | 0.00 | 0.18 |
Relative risk | 18.15 | 3.88 | 84.90 |
Odds ratio | 186.20 | 28.42 | 1220.14 |