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Table 9 Diagnostic accuracy of CESM tested in patients with ACR grade C/D versus the result of biopsy or follow-up as the gold standard for lesion classification

From: Contrast-enhanced spectral mammography: successful initial clinical institute experience

Lesion classification by SMG Final diagnosis  
Malignant Benign Total
Probably malignant (BIRADS 4–6) 49 5 54
Probably benign (BIRADS 1–3) 1 19 20
Total 50 24 74
Statistic Value Lower bound (95%) Upper bound (95%)
Correct classification 92% 86% 98%
Misclassification 8% 2% 14%
Sensitivity 98% 88% 100%
Specificity 79% 59% 91%
False positive rate 21% 6% 36%
False negative rate 2% 0% 6%
Prevalence 68% 57% 78%
Positive predictive value (PPV) 91% 83% 98%
Negative predictive value (NPV) 95% 85% 100%
Positive likelihood ratio (LR+) 4.70 2.15 10.27
Negative likelihood ratio (LR−) 0.03 0.00 0.18
Relative risk 18.15 3.88 84.90
Odds ratio 186.20 28.42 1220.14
  1. Data in cross-tables are counts