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Table 3 Comparison of the studied ratios at various studied sites according to Sarnat staging

From: Magnetic resonance imaging and spectroscopy in evaluation of hypoxic ischemic encephalopathy in pediatric age group

  HIE staging One -Way ANOVA   
Stage I Stage II Stage III F P value P1 P2 P3
Basal ganglia   
 lac/Cr ratio Mean ± SD 0.19 ± .02 0.83 ± .42 2.79 ± .33 406.87 < 0.001* 0.003* < 0.001* < 0.001*
 NAA/Cr ratio Mean ± SD 1.06 ± .01 0.84 ± .10 0.56 ± .04 975.09 < 0.001* < 0.001* < 0.001* < 0.001*
 NAA/Cho ratio Mean ± SD 0.39 ± .02 0.3 ± .05 0.17 ± .03 159.43 < 0.001* < 0.001* < 0.001* < 0.001*
 Cho/Cr ratio Mean ± SD 2.92 ± .34 2.94 ± .23 3.15 ± .26 2.77 0.101 Not applicable
Thalamus          
 lac/Cr ratio Mean ± SD 0.2 ± .04 0.92 ± .49 3.04 ± .50 223.76 < 0.001* 0.003* < 0.001* < 0.001*
 NAA/Cr ratio Mean ± SD 1.07 ± .01 0.84 ± .11 0.56 ± .05 640.92 < 0.001* < 0.001* < 0.001* < 0.001*
 NAA/Cho ratio Mean ± SD 0.4 ± .01 0.28 ± .03 0.18 ± .02 351.74 < 0.001* < 0.001* < 0.001* < 0.001*
 Cho/Cr ratio Mean ± SD 2.88 ± .31 2.91 ± .23 3.15 ± .26 3.34 0.068 Not applicable
Frontal WM          
 lac/Cr ratio Mean ± SD 0.18 ± .03 0.97 ± .49 2.94 ± .38 358.51 < 0.001* 0.002* < 0.001* < 0.001*
 NAA/Cr ratio Mean ± SD 1.10 ± .02 0.83 ± .17 0.57 ± .04 765.59 < 0.001* 0.002* < 0.001* 0.002*
 NAA/Cho ratio Mean ± SD 0.41 ± .01 0.31 ± .04 0.18 ± .03 228.16 < 0.001* < 0.001* < 0.001* < 0.001*
 Cho/Cr ratio Mean ± SD 2.87 ± .30 2.91 ± .22 3.08 ± .17 2.92 0.095 Not applicable
Occipital WM          
 lac/Cr ratio Mean ± SD 0.25 ± .09 0.9 ± .49 3.09 ± .45 249.05 < 0.001* 0.005* < 0.001* < 0.001*
 NAA/Cr ratio Mean ± SD 1.11 ± .02 0.82 ± .09 0.46 ± .01 2871.11 < 0.001* < 0.001* < 0.001* < 0.001*
 NAA/Cho ratio Mean ± SD 0.4 ± .02 0.31 ± .02 0.17 ± .03 184.80 < 0.001* < 0.001* < 0.001* < 0.001*
 Cho/Cr ratio Mean ± SD 3.03 ± .29 3.04 ± .20 3.15 ± .26 .858 0.447 Not applicable
  1. *Significant at p < 0.05