Fig. 7
A male patient aged 27 years, known to have RRMS with EDSS score of 3.5. White matter lesions segmentation: T2 FLAIR images in sagittal, coronal, and axial planes; a raw unprocessed image showing white matter hyperintense lesions located at the periventricular and white matter, b T2 FLAIR image after registration to MNI template and c processed T2 FLAIR image with segmented white matter lesions. Deep grey matter structures segmentation: T1W images in sagittal, coronal and axial planes; d raw unprocessed T1W images, e T1W images after registration to MNI template, and f and g T1W images with coloured segmented grey matter structures with thalamus in orange, caudate in red, putamen in green, and hippocampus in blue. Grey matter structures volumes after correction for ICV: Left and right thalamus: 0.00395 and 0.00321 cm3, left and right caudate: 0.00275 and 0.00273 cm3, left and right putamen: 0.00262 and 0.00261 cm3, left and right hippocampus: 0.00229 and 0.00263 cm3. White matter lesions volume: 1.7 cm3. We found that the patient had a significant decrease in the volumes of the putamen bilaterally, right thalamus, and left hippocampus, and he had white matter lesions volume of 1.7 cm3 and EDSS score of 3.5