Fig. 4

A high-risk 35-year-old female with dense breasts. a Bilateral digital mammogram craino-caudal views that showed extremely dense breasts, BI-RADS zero. b Bilateral CEM, craino-caudal views that showed right breast lower outer faint asymmetrical regional non-mass contrast uptake of nodular pattern (arrow heads), BI-RADS 3 and left breast deep central faintly enhancing circumscribed focal tiny mass (long arrow), BI-RADS 2. c Early series of DCE-MRI and d Three-dimensional post-contrast maximum intensity projection images. According to MRI findings, there was right breast obvious non-mass clumped contrast uptake, suspicious of malignancy, BI-RADS 4c and left breast deep central benign looking tiny enhancing mass, BI-RADS 2. Based on MRI, biopsy was requested for the right breast non-mass enhancement, and the pathology result was benign proliferative disorder (fibrocystic changes and papillomatosis)