Skip to main content

Table 2 Diagnostic accuracy of magnetic resonance imaging (MRI) parameters to predict hepatic steatosis with the best predictive cutoffs

From: Quantitative MDCT and MRI assessment of hepatic steatosis in genotype 4 chronic hepatitis C patients with fibrosis

  AUC (95% CI) SE SP PPV NPV  + LR − LR p
For the prediction of liver steatosis
T1-fat fraction > -13.7% 0.808 (0.637–0.922) 66.7 90 94 53.5 6.7 0.4 < 0.001
Fat percentage (> 5.1%) 0.702 (0521–0.846) 54.2 80 86.4 42.7 2.7 0.6 0.030
Proton density fat fraction (> 4.95%) 0.958 (0.828–0.995) 95.8 90 95.7 90.1 9.6 0.1 < 0.001
For the prediction of mild liver steatosis
T1-fat fraction > −13.7% 0.845 (0.622–0.963) 72.7 90 74.4 89.2 7.3 0.3 < 0.001
Fat percentage (> 5.1%) 0.650 (0.414–0.841) 45.5 80 47.7 78.6 2.3 0.7 0.217
Proton density fat fraction (> 4.95%) 0.910 (0.701–0.987) 91 90 78.5 96.1 9.1 0.1 < 0.001
For the prediction of moderate liver steatosis
T1-fat fraction (> 0.4%) 0.654 (0.466–0.812) 27.3 100 100 77.4 0.7 0.147
Fat percentage (> 2.8%) 0.652 (0.463–0.810) 90.9 38.1 37 91.3 1.5 0.2 0.154
Proton density fat fraction (> 8.44%) 0.931 (0.782–0.988) 100 85.7 73.7 100 7 0 < 0.001
For the prediction of severe liver steatosis
T1-fat fraction (> 6.2%) 0.619 (0.445–0.773) 40 100 100 91.8 0.6 0.942
Fat percentage (> 6.1%) 0.850 (0.694–0.945) 100 65.6 30.3 100 2.9 0 0.0742
Proton density fat fraction (> 20.4%) 0.975 (0.861–995) 100 93.8 70.7 100 16 0 < 0.001
  1. AUC area under the receiver operating characteristic curve, + LR positive likelihood ratio, − LR negative likelihood ratio, NPV negative predictive value, PPV positive predictive value, SP specificity, SE sensitivity