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Fig. 5 | Egyptian Journal of Radiology and Nuclear Medicine

Fig. 5

From: Chemotherapy-related neurotoxicity in pediatric cancer patients: magnetic resonance imaging and clinical correlation

Fig. 5

A 5-year-old male diagnosed as acute lymphoblastic leukemia on day 17 of his chemotherapy protocol (IV vincristine, IV doxorubicin, IV l-asparaginase, oral prednisone and intrathecal methotrexate, hydrocortisone, ARA C), he presented with convulsions, and MRI was done at the same day after the clinical presentation. MRI revealed: total thrombosis of superior sagittal sinus, cortical veins, right and left transverse sinuses as well as straight sinus showing high signal on T1 SE (a) (short black arrow), loss of signal void on T2 (b) (long black arrow), isointense signal on FLAIR (c) (short white arrow), low signal on T2* (d) (white arrowhead) and non-visualization of occluded veins or sinuses on MRV (f1, f2) (white arrows). The thrombosed sinuses are not detected on T1 post-contrast (e1, e2) (black arrowhead) and DWI and ADC images (not shown). There were also bilateral acute frontal hemorrhagic venous infarctions (black arrows in d)

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