Fig. 5From: Erdheim–Chester disease: with neurological manifestation and multisystem involvement: case report and radiological reviewRadiographs of a 60-year-old male patient diagnosed with Erdheim–Chester disease reveals regions of diffuse sclerosis with loss of cortico-medullary differentiation in diaphysis and metaphysis of right femur (A, B) and tibia (C) with bone within bone appearance. Computed tomography of the brain reveals ill-defined areas of sclerosis in the calvarium (D, E)Back to article page