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Table 6 Validity of FA, ADC and MD in differentiating endometrial carcinoma grades

From: Use of diffusion-weighted imaging and diffusion tensor imaging in assessment of myometrial invasion in patients of endometrial carcinoma and its correlation with histopathological grading (Prospective study)

  AUC (95% CI) P value Cutoff point Sensitivity % Specificity% PPV% NPV% Accuracy%
Grade 3 from grade 1 or 2 endometrioid adenocarcinoma
DT-FA 0.942
(0.860–1.0)
 < 0.001* 0.236 90.9 96.4 90.9 96.4 94.9
DT-MD 0.894
(0.793–0.99)
 < 0.001* 0.825 81.8 82.1 64.3 92.0 84.6
DW-ADC 0.894
(0.793–0.996)
 < 0.001* 0.916 90.9 64.3 50.0 94.7 74.4
Grade 2 or 3 from grade 1 endometrioid adenocarcinoma
DT-FA 0.980
(0.947–1.0)
 < 0.001* 0.335 94.4 85.7 85.0 94.7 90.0
DT-MD 0.918
(0.81–1.0)
 < 0.001* 0.983 88.9 90.5 88.9 90.5 89.7
DW-ADC 0.884
(0.774–0.99)
 < 0.001* 0.941 77.8 85.7 82.4 81.8 84.6
  1. *Highly significant
  2. AUC area under curve, CI confidence interval, NPV negative predictive value, PPV positive predictive value