Fig. 3

A female patient aged 24 years old, known to have RRMS with EDSS score of 3. I. Cortex segmentation: raw T1WI axial plane (A), T1W image after brain extraction (B), gray and white matter segmentation (C) and cortex segmentation (D). II. Surface reconstruction: T1W image with pial surface (red line) and white matter surface (yellow line) (E) and surface reconstruction (F). III. Cortical thickness results in mm: The patient had significant decrease in the mean cortical thickness (1.848 mm, 1.944 mm), and the precentral (1.7775 mm, 1.8151 mm), postcentral (1.3831 mm, 1.4447 mm), paracentral (1.7146 mm, 1.8118 mm) and posterior cingulate cortices (1.7551 mm, 1.7117 mm) in left and right side, respectively